The Third Global High-Level Ministerial Conference on Antimicrobial Resistance, hosted in Muscat, Oman, concluded today, where targets to address the global antimicrobial resistance (AMR) challenge were discussed for the first time. The conference and its numerical targets for antimicrobial use in the human and animal sectors will pave the way for bold political commitments at the forthcoming UN General Assembly High-Level Meeting on AMR in 2024.

The conference agreed the Muscat Ministerial Manifesto, which sets out the three global targets:

· Reduce the total amount of antimicrobials used in agrifood systems by at least 30-50% by 2030, galvanizing national and global efforts;

· Preserve critically important antimicrobials for human medicine, ending the use of medically important antimicrobials for growth promotion in animals;

· Ensure ‘Access’ group antibiotics (a category of antibiotics that are affordable, safe and have a low AMR risk) represent at least 60% of overall antibiotic consumption in humans by 2030.

Globally agreed targets will be key to protecting the efficacy of antimicrobials and curbing the development of AMR worldwide, as well as reducing environmental pollution, in turn lowering the spread of AMR.

Countries also made commitments to implement National Action Plans for AMR and strengthen surveillance through improved data reporting and management, private sector engagement and implementation of evidence-based practices.

The Food and Agriculture Organization of the United Nations (FAO), the UN Environment Programme (UNEP), the World Health Organization (WHO) and the World Organisation for Animal Health (WOAH, founded as OIE), known as the Quadripartite, welcome the outcomes of the Conference for accelerating action on AMR.

The COVID-19 pandemic may have constrained global efforts to address AMR, but it has also demonstrated the critical links between humans, animals and the environmental ecosystem. A range of stakeholders – including the health care, pharmaceutical, veterinary, food safety, agricultural, environmental sectors – have a shared responsibility to continue to collectively respond to AMR.

“FAO recognizes the importance of reducing the need for antimicrobials on farms and will soon launch a global 10-year initiative to provide comprehensive support to Members focusing on transforming agrifood systems to contribute to this reduction,” said FAO Director-General QU Dongyu.

“Self-reporting by countries indicates that a third of National Action Plans on AMR do not include the environment. This signals the critical importance of supporting countries to boost actions to prevent and reduce environmental pollution. The burden of AMR can be reduced if we focus on all its dimensions and work together. UNEP is committed to working with Member States and key partners, including the Quadripartite organizations, to address AMR,” said Under-Secretary-General of the United Nations and Executive Director for UNEP Inger Andersen.

"Antimicrobial resistance is one of the most urgent and complex challenges of our time, and yet perhaps because it is not as dramatic as a pandemic, a war or a humanitarian emergency, it doesn’t attract the same attention," said WHO Director-General, Dr Tedros Adhanom Ghebreyesus. "It is my firm hope that this meeting will pave the way towards bold - and concrete - political commitments at the 2024 UN General Assembly High Level Meeting on AMR."

“The use of antimicrobials in animals has shown an overall decrease over the last years. By strengthening biosecurity and husbandry practices, such as animal vaccination, we can further build on this great achievement and sustainably reach the agreed goals,” said WOAH Director General Dr Monique Eloit. “Reducing the need for antimicrobials is the best way to prevent antimicrobial resistance.”

The conference marks the conclusion of World Antimicrobial Awareness Week, an annual week-long global campaign that brings together leaders across sectors to highlight the actions needed to preserve and protect antimicrobials.

As highlighted by the Manifesto, the Quadripartite will continue to scale up support through a One Health approach, which balances and optimizes the health of people, animals, plants and ecosystems. The partnership will also continue to coordinate a global, multisectoral AMR response, promote strong governance and leadership, and support countries in developing and implementing National Action Plans on AMR.

About the Quadripartite organizations:

About the Food and Agriculture Organization of the United Nations (FAO)

FAO is a specialized agency of the United Nations that leads international efforts to defeat hunger. Its goal is to achieve food security for all and make sure that people have regular access to enough high-quality food to lead active, healthy lives. With 195 members - 194 countries and the European Union, FAO works in over 130 countries worldwide.

For more information please contact:

Peter Mayer, FAO News and Media, peter.mayer@fao.org

About the UN Environment Programme (UNEP)

UNEP is the leading global voice on the environment. It provides leadership and encourages partnership in caring for the environment by inspiring, informing and enabling nations and peoples to improve their quality of life without compromising that of future generations.

For more information, please contact:

Keishamaza Rukikaire, Head of News & Media, UN Environment Programme

About the World Health Organization (WHO)

Dedicated to the well-being of all people and guided by science, the World Health Organization leads and champions global efforts to give everyone, everywhere an equal chance to live a healthy life.

About WHO

The World Health Organization provides global leadership in public health within the United Nations system. Founded in 1948, WHO works with 194 Member States, across six regions and from more than 150 offices, to promote health, keep the world safe and serve the vulnerable. Our goal for 2019-2023 is to ensure that a billion more people have universal health coverage, to protect a billion more people from health emergencies, and provide a further billion people with better health and wellbeing.